Debdyuti (Deb) Roy is a Ph.D. candidate in Biophysics at the University of California, Davis School of Medicine, working at the intersection of neurodevelopmental disorders, membrane and cellular physiology, and translational neuroscience.

Her research focuses on defining how disease-associated genetic changes alter neuronal structure and network function using primary mouse neuron cultures, high-density multielectrode array (HD-MEA) electrophysiology, immunocytochemistry, and molecular and genetic approaches. She is particularly interested in linking gene dosage and molecular regulation to circuit-level dysfunction in disorders such as Dup15q syndrome and Angelman syndrome.

Her work spans primary neuronal culture, network electrophysiology, protein and gene-expression analysis, and emerging human cellular models including induced pluripotent stem cell (iPSC)-derived neurons, with future plans to incorporate brain organoid systems for cross-species and developmental comparisons. Broadly, her goal is to build a translational bench-to-bedside framework that connects molecular mechanisms to clinically relevant phenotypes and therapeutic response, helping advance precision treatments for neurodevelopmental disorders.