I have a passion for neuroscience and a great interest in the neuropharmacology that drives wakefulness and sleep. At Roche NRD, I am working as a senior scientist focused on sleep biomarkers, where I plan clinical ph1 and ph2 trials, work on protocols, ICFs, synopsis, FDA/EMA briefing packages, site material for biomarker implementation, monitoring and analyses of incoming biomarker data (e.g. PSG, actigraphy, diaries and sleep scales)from clinical trials.
As a junior group leader with Nedergaard and Moos-Knudsen labs the University Hospital Copenhagen I focused on ultrafast magnetic resonance imaging of sleep and wakefulness and associated effects on brain fluid motion. I ran a placebo-controlled clinical trial MR/sleep study in healthy controls and investigated efects of adrenergic antagonist on Alzheimer's via the Danish national registry together with my students.
During my PhD and postdoc at the University of Zurich in Switzerland, I investigated the pharmacology of sleep-wake regulation and ran several clinical human sleep-deprivation studies where I examined the effects of caffeine, modafinil and tolcapone on sleep and wakefulness. I also performed MR and PET neuroimaging studies investigating metabolic and neuroreceptor changes in the brain induced by sleep loss.
My current position, I have a background in biomedical engineering from the Technical University of Denmark and the University of Copenhagen in the field of physiology, physiological modeling and statistical data processing
Specialties: Cross disciplinary research related to sleep physiology, neuroscience, mathematical modeling and data processing. Especially focused on sleep, MR and PET neuroimaging, and the sleep EEG.
