Children and adults with Angelman Syndrome (AS) demonstrate a wide variety of movements that may negatively impact quality of life. At early ages, seizures and epileptic myoclonus are common, as are more benign movements seen in typically developing children, such as stereotypy. Starting in the teen years, the incidence of dystonia and nonepileptic myoclonus increases. The clinical picture may be complicated by the presence of multiple abnormal movements, varied presentations of these movements, and concurrent seizures. Using a revised survey combined with video data, we continue to explore factors that contribute to movement disorders in AS. In a cohort of 23 patients for which survey and video data were available, 78% demonstrated myoclonus, 57% dystonia, and 52% had both myoclonus and dystonia. Tremor was not identified in the video examples, despite being reported by 30% of respondents. In this video cohort, reported triggers were consistent with our prior data, with stress, poor sleep, sitting to standing, constipation, fever, and menses in women being key triggers. Sleep was the only feature to make abnormal movements better in more than 50% of respondents. We hypothesized that exposure to antipsychotic medications may contribute to abnormal movements later in life. In this cohort of 23 subjects, one was on quetiapine and one was on risperidone, both for greater than 1 year, representing exposure in 9% of this cohort. Additional data on the quantitation of abnormal movements in AS will be reported.